Aurigene is a Bangalore based world-class drug discovery company with integrated capabilities for discovery and development of novel small molecule drugs.Aurigene provides Drug Discovery Services for Lead Generation/ Lead Optimization. The Business Model involves collaborative Drug Discovery with partners, on a risk- and reward-sharing basis. Typical Aurigene projects involve starting with a partner’s target protein and delivering an Optimized Lead, ready to go into clinical development.Aurigene employs both Structure Guided Drug Design (SGDD) and conventional Screening technologies for Drug Discovery. SGDD involves structural screening, computational chemistry aided ligand design, mining and screening of novel chemical entities, thus providing direction for Lead Discovery and Medicinal Chemistry. Early animal work involving ADME and Toxicity improves the probability of success. The approach helps in identifying the challenges at a very early stage and helps in setting a road map for the next steps in the process, thus shortening the overall project timelines and thereby mitigating risks.

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